EC50 values for dasatinib-induced dephosphorylation of BCR-ABL and SFKs.
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Cells were incubated for 2 h with dasatinib at different concentrations and the levels of phosphorylated kinases were then determined by western-blotting using phospho-specific antibodies. Relative values (% of controls) from at least 3 independent experiments were merged and the summary results were fitted with sigmoidal dose-response curves using GraphPad Prism 5.0 software. The table shows the obtained EC50 values along with 95% confidence interval. In case of JURKAT cells, bands corresponding to p-HCK and p-LYN were also evaluated separately.EC50 values for dasatinib-induced dephosphorylation of BCR-ABL and SFKs.
创建时间：
2015-12-02
