Reactivity of Homo- and Hetero-bimetallic Reagents Towards C–F Activation

This research focuses on developing cleaner and more sustainable ways to break and transform carbon-fluorine (C–F) bonds, which are among the strongest in organic molecules. These bonds are common in pharmaceuticals, agrochemicals, and industrial materials, yet are difficult to modify using traditional methods. I explored how simple, earth-abundant metals such as magnesium and sodium can activate these tough bonds without relying on expensive or toxic transition metals. In addition, this research explored the use of mechanochemistry (ball mill) to drive some of these transformations with little or no solvent. This work opens new pathways for greener chemical manufacturing.