These human cell line, mice and rat data belong to a study that additionally comprises of 80 human cardiac translatomes. The human data have been submitted to the European Genome-Phenome Archive, ega-
Deletion of Lmna, encoding nuclear membrane protein LMNA, specifically in mouse cardiac myocytes activates BRD4 and leads to heart failure, arrhythmias, myocardial fibrosis, apoptosis, and premature d
Table S2. RNAseq quality control table. Raw read counts ranged from ~â 36 to 66 million. Read counts show a 99% retention after base quality control and a 94â 96% alignment rate. (XLSX 16Â kb)
Atherosclerosis and pressure overload are major risk factors for the development of heart failure in patients. Cardiac hypertrophy often precedes the development of heart failure. However, underlying