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Crystal structure of EGFR_TMX in complex with covalently bound fragment 8

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Protein Data Bank Japan2024-11-13 更新2026-05-23 收录
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Crystal structure of EGFR_TMX in complex with covalently bound fragment 8 Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, DIMETHYL SULFOXIDE, Epidermal growth factor receptor, ... Authors: Dokurno, P. Deposit date: 2022-12-26 Release date: 2023-12-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase. Rsc Med Chem, 14, 2023

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2022-12-26
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