Genetic association in the trio cohort.

A total of 66 SNPs were genotyped in the linked region on chromosome 16 and subsequently analyzed with TDT. The table shows a subset of these located around ABAT. T:U denotes the number of transmitted versus untransmitted alleles. p-val is the nominal p value. padj is the p-value adjusted for multiple testing through permutation analysis for the full 66 SNP panel. The trio cohort consists of 177 probands with positive findings from endoscopy evaluation and 175 probands with positive findings from histology evaluation. In total the cohort consist of 219 trios. The eight SNPs marked with an asterisk were also genotyped in the adult case control cohort in addition to rs8046201.