Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex

Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex Descriptor: (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone, 5-hydroxytryptamine receptor 1A, ... Authors: Schneider, J, Gmeiner, P, Hove, T.T, Rasmussen, T, Boettcher, B. Deposit date: 2023-06-27 Release date: 2024-05-29 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Discovery of a functionally selective serotonin receptor (5-HT 1A R) agonist for the treatment of pain. Sci Adv, 11, 2025