Significant SNPs at α = 0.05 in the logistic regression main effect models.

MAF(a), minor allele frequency); pHWE, p-value from the Hardy Weinberg equilibrium test; MOI, Mode of Inheritance. Repr. (%), percentage reproducibility assessing the robustness of each SNP by LASSO. All models are adjusted for age, gender, region and smoking status. Odd ratio and 95%CI under the model of inheritance that provided the lowest p-value, and percentage reproducibility from LASSO under the additive mode of inheritance.