PHAROS
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Pharos is the user interface to the Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) program funded by the National Institutes of Health (NIH) Common Fund. (Grant No. 1U24CA224370-01). The goal of KMC is to develop a comprehensive, integrated knowledge-base for the Druggable Genome (DG) to illuminate the uncharacterized and/or poorly annotated portion of the DG, focusing on three of the most commonly drug-targeted protein families: G-protein-coupled receptors (GPCRs) ; Ion channels (ICs) and Kinases.
Pharos是由美国国立卫生研究院(National Institutes of Health, NIH)共同基金资助的「可靶向基因组照亮计划(Illuminating the Druggable Genome, IDG)」的知识管理中心(Knowledge Management Center, KMC)的用户界面。(资助编号:1U24CA224370-01)。该知识管理中心的目标是构建一套面向可靶向基因组(Druggable Genome, DG)的综合性集成知识库,旨在阐明可靶向基因组中未被表征或注释不足的部分,重点聚焦于三大最常见的药物靶向蛋白质家族:G蛋白偶联受体(G-protein-coupled receptors, GPCRs)、离子通道(Ion channels, ICs)以及激酶(Kinases)。




