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Effects of PP2Ac over-expression on mouse naïve CD4 T cell gene profile upon activation

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NIAID Data Ecosystem2026-03-11 收录
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A transgenic mouse was generated using a CD2-driven transgene containing the cDNA of Ppp2ca to achieve over-expression of PP2Ac in T cells. Naïve CD4 T cells were isolated and lysed at times 0, 6, and 24 hours after stimulation with anti-CD3 and anti-CD28 Naïve CD4 T cells from wild type mice were compared with naïve CD4 T cells from PP2Ac transgenic mice

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2019-03-04
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