Additional file 2 of Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atrophic gastritis

Supplementary Material 2: Additional file 2: Figure S2. Expression of classic markers in each T-cell subcluster and inferred TF activities of T-cell subclusters. (A) Bubble plot depicting the average expression levels and cellular fractions of selected stress-related heat shock marker genes in 3 defined T-cell subclusters. (B) Bubble plot depicting the average expression levels and percentages of exhaustion-related marker genes in 3 defined T-cell subclusters. (C) Bubble plot depicting the average expression levels and cellular fractions of effector function-related marker genes in 3 defined T-cell clusters. (D) Heatmap showing TF activity among different T-cell subclusters. (E) Heatmap showing TF activity among different T-cell subclusters in the CAG and control groups. CD4+ Tex: exhausted CD4+ T-cell subtype, CD8+ Tef: CD8+ T effector cell subtype, CD8+ Tsr: CD8+ T stress response.