Three-Component Heterocyclization of gem-Bromofluorocyclopropanes with NOBF4: Access to 4‑Fluoropyrimidine N‑Oxides
收藏数据链接：
官方服务：
资源简介：
Novel three-component heterocyclization involving gem-bromofluorocyclopropanes, nitrosyl tetrafluoroborate, and a molecule of the solvent (nitrile) yielding previously unknown fluorinated pyrimidine N-oxides is described. A two-step synthetic approach to 4-fluoropyrimidine N-oxides from alkenes under mild conditions is developed using this reaction. Mechanistic aspects of the heterocyclization are discussed.
创建时间：
2016-02-20
