This project reveals the role of Gcn4 in methionine dependent regulation of anabolic response. Using ChIP seq and RNA seq approaches, we identify the direct and indirect targets of Gcn4 under methioni
Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, soaked with allosteric activators AMP and Glucose 6-Phosphate Descriptor: 6-O-phosphono-alpha-D-glucopyranose,
Cold and nutrient activated brown adipose tissue (BAT) is capable of increasing systemic energy expenditure via uncoupled respiration and secretion of endocrine factors thereby protecting mice against
In early mouse embryogenesis, the distinct enrichment of α-ketoglutarate (αKG) in blastocysts and L-2-hydroxyglutarate (L-2HG) in 2-cell (2C) embryos serves as a key metabolic signature. While elevate
