To elucidate the roles of YAP and FOS/AP-1 in driving OnF reporgramming, we tested the effects of their ecotpic expression in healthy intestinal organoids. The sequential overperession recapitulates t
To investigate the physiological role of BH4 in cardiac function, we developed mice with cardiomyocyte-specific deletion of (cm)Gch1, the gene that encodes for GTPCH, which responsible for de novo syn
To investigate the biological role of Gdown1, differentially expressed genes in Gdown1 knockout and p53/Gdown1 double-knockout mouse liver were analyzed by RNA-seq. Overall design: To investigate diff