Human mesenchymal stem cells (hMSCs), residing in bone marrow as well as in the synovial lining of joints, can be triggered to differentiate toward chondrocytes. Thus, hMSCs harbor great therapeutic p

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Data-Independent Acquisition-Based Quantitative Proteomics for Pairwise Comparison of Serum and Plasma

定量蛋白质组学

生物标志物发现

Human blood contains proteins secreted by various organs, but there is no consensus on whether serum or plasma is preferable for proteome studies. Mass spectrometry employing data-independent acquisit

Figshare2025-05-22 更新20

Isobaric Tagging and Data Independent Acquisition as Complementary Strategies for Proteome Profiling on an Orbitrap Astral Mass Spectrometer

定量蛋白质组学

质谱技术比较

Comprehensive global proteome profiling that is amenable to high throughput processing will broaden our understanding of complex biological systems. Here, we evaluate two leading mass spectrometry tec

Figshare2025-02-12 更新40

Evaluation of Advanced Precursor Determination for Tandem Mass Tag (TMT)-Based Quantitative Proteomics across Instrument Platforms

定量蛋白质组学

质谱数据分析

Tandem mass tag (TMT)-based quantitation is a strong modality for quantitative proteomics, as samples can be multiplexed, creating large-scale data sets with high precision and minimal missing values.

Figshare2018-10-31 更新30

Mainye et al - SILAC data pheromone response

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