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Structure of PAK2 in complex with compound 12

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Protein Data Bank Japan2025-07-16 更新2026-05-23 收录
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https://pdbj.org/mine/summary/9d51
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Structure of PAK2 in complex with compound 12 Descriptor: N~2~-{[(1s,4s)-4-aminocyclohexyl]methyl}-N~4~-[5-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidine-2,4-diamine, PAK-2p34 Authors: Cakici, O, Suto, R.K, Olland, A.M. Deposit date: 2024-08-13 Release date: 2025-04-02 Last modified: 2025-07-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2. Bioorg.Med.Chem.Lett., 127, 2025
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2024-08-13
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