Summary of adherence mutant properties.

Footnotes: aThese columns list each mutant according to the mutated gene (orf19 numbers and gene names). bS. cerevisiae orthologs or best hits, or transcription factor classes, are indicated as listed in the Candida Genome Database. cColumn that indicates whether a deletion transcription factor mutant was available for adherence testing. All deletion mutants were created in the SN152 parent strain as described in Homann et al. 2009. dColumn that indicates whether a deletion transcription factor mutant was created and test for adherence. Strains were created in the BWP17 background and genotypes are in Table S4. eThese columns list the relative adherence for each mutant strain, and for each mutant strain derivative that carries the ZAP1-OE allele. The complete dataset for adherence measurements is in Table S1. All of the mutants and ZAP1-OE strains were insertion homozygotes except for ace2, arg81, bcr1, crz2, snf5, and zfu2, which were deletion homozygotes. fThis column lists the number of genes that were differentially expressed in each mutant compared to the wild-type control strain DAY185, as indicated by nanoString profiling. A cutoff p value of 0.05 was applied. Complete data and p values are in Table S2.