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Approaches to Managing Periferal Nerve Lesions of the Arm and Forearm Actual Treatment and Literature Review

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Zenodo2024-01-29 更新2026-04-07 收录
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Peripheral nerve injuries are frequently seen in clinical practice, and the absence of a readily accessible algorithm for achieving favorable treatment outcomes is a recurrent challenge. The frequency of incomplete injuries is most prevalent. Seddon's classification system classified nerve damage into three distinct groups, namely neurapraxia, axonotmesis, and neurotmesis. Following a full axonal transection, the neuron experiences a series of degenerative mechanisms, subsequently followed by endeavors at regeneration. The distal growth cone actively strives to establish connections with the degraded distal fiber. The prevailing surgical practice involves employing a nylon suture for epineural repair. Nerve-cable interfascicular autografts are utilized to address gaps that cannot be effectively bridged by primary repair due to severe stress. Extensive research is currently being conducted on pharmacologic drugs, immune system modulators, boosting factors, and entubulation chambers. The ongoing advancements resulting from these investigations hold promise for enhancing the outcomes of nerve injury treatment in clinical settings

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2024-01-29
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