RNA-seq revealed the mechanism of hexyl-aminolevulinate ethosomes against Candida albicans biofilm

Candida albicans is prone to form highly drug-resistant biofilms that render conventional treatments ineffective, thereby resulting in chronic and recurrent infections. In our previous studies, we found that HAL-ES is a promising anti-biofilm drug. To further investigate the mechanism of HAL-ES anti-biofilm activity, RNA-seq was used to analyze the alterations at the transcript level.