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Concise Synthesis of the Oxapentacyclic Core of Cortistatin A

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NIAID Data Ecosystem2026-03-06 收录
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A concise synthetic approach for constructing the oxapentacyclic framework of cortistatin A is described. The synthesis features a furan−oxyallyl [4 + 3] cycloaddition and double-intramolecular aldol reactions. In addition, an interesting core structure was obtained in 11 steps from furan by using our method.

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2010-11-19
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