In order to respond reliably to specific features of their environment, sensory neurons need to integrate multiple incoming noisy signals. Crucially, they also need to compete for the interpretation o
We are imaging ~100000 neurons using a custom built light sheet microscope, enabling us to observe the activity of each neuron individually during rest periods with no stimulation, and during visual s
Data set related to the study published by Miguel-Quesada et al, 2023 showing the role of cortical astrocytes on sensory information processing. All data are related to the figures shown in the study
Neural processing rests on the intracellular transformation of information as synaptic inputs are translated into action potentials. This transformation is governed by the spike threshold, which depen
Layer (L) 2/3 pyramidal neurons in the primary somatosensory cortex (S1) are sparsely active, spontaneously and during sensory stimulation. Long-range inputs from higher areas may gate L2/3 activity.