Hepatic RNA expression profile analysis of antibiotics treated and untreated Clonorchis sinensis-infected mice. Hepatic RNA expression profile analysis of antibiotics treated and untreated Clonorchis sinensis-infected mice

Study whether IL-33 participates in the cholangiopathies during C. sinensis infection,and whether the gut microbiota participates in the pathogenesis of clonorchiasis Overall design: we performed transcriptional profiling analysis by RNA sequencing of liver RNA isolated from antibiotics treated and untreated 35 days post C. sinensis-infected WT and IL-33-/- mice,in quadruplicate,using Illumina HiSeq X-TEN