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A phase Ib/II Study of Palbociclib in Combination with Bazedoxifene in Hormone Receptor Breast Cancer

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NIAID Data Ecosystem2026-03-14 收录
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In this phase Ib/II clinical trial, the investigators evaluated the efficacy and safety of the combination of palbociclib with bazedoxifene in patients with a metastatic endocrine-resistant hormone receptor-positive, HER2-negative breast cancer. Furthermore, whole exome sequencing of cell-free tumor DNA was done on serial samples from these patients, revealing potential molecular changes associated with mechanisms of resistance.

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2022-12-16
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