The goal of this project is to generate transcriptome profiling of Lgr5-GFP high intestinal stem cells (High)/Lgr5-GFP low progenitors (Low) and CD24+C-kit+ Paneth (PA) cells for a systemic analysis o
The analysis of IBDMDB samples is presented in this file as follows: Sheet 1: Features selected for human HSPs and meta transcripts. Sheet 2: Selected host and meta transcriptomic samples. Sheets 3 an
Bulk RNAseq of sigmoid colon biopsies from healthy volunteers and ulcerative colitis patients. Subjects were treated with Placebo or IL-22Fc at different doses, and biopsies were collected at day 0 an
Anti-inflammatory properties of omega 3 polyunsaturated fatty acids (PUFA) have been exploited in the prevention and management of inflammatory bowel diseases (IBD) with promising results. However, it
We augmented the Zinc carboxypeptidase A1 (CP, AGAP009593) gene of the malaria mosquito Anopheles gambiae to secrete the exogenous antimicrobial peptides Magainin 2 and Melittin, and to enable non-aut