Helleday HRAS Project

NIAID Data Ecosystem2026-03-10 收录

癌症突变特征

RAS基因突变

数据链接：

https://www.omicsdi.org/dataset/ega/EGAS00001000332 数据链接链接失效反馈

官方服务：

资源简介：

This experiment is looking at the mutational signatures generated by engineered HRAS mutations by using whole genome sequence generated on massively parallel next generation sequencers.EGA study EGAS00001000332

创建时间：

2017-07-26

Fitted values for exposure to each of the 8 signatures (including the background signature) discovered by applying SparseSignatures to breast cancer data, of each of the 560 whole genomes in the dataset.

癌症突变特征

肿瘤基因组学

(XLSX)

NIAID Data Ecosystem40

Germline NRAS mutation causes a novel human autoimmune lymphoproliferative syndrome

自身免疫性淋巴增殖综合征

RAS基因突变

The p21 RAS subfamily of small GTPases, including KRAS, HRAS, and NRAS, regulates cell proliferation, cytoskeletal organization and other signaling networks, and is the most frequent target of activat

NIAID Data Ecosystem40

Mutational_signatures_in_carcinogen_induced_mouse_liver_tumours. Mutational_signatures_in_carcinogen_induced_mouse_liver_tumours

癌症突变特征

肿瘤基因组学

Human cancers arise through the combined effect of environmental exposures and endogenous mutagenesis resulting from factors such as replication stress and metabolism. Mouse and human tumour genome an

NIAID Data Ecosystem30

A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

癌症突变特征

体细胞突变模式

Recent advances in sequencing technologies have enabled the production of massive amounts of data on somatic mutations from cancer genomes. These data have led to the detection of characteristic patte

NIAID Data Ecosystem40

Single base substitution mutational signatures in pediatric acute myeloid leukemia based on whole genome sequencing

癌症突变特征

血液肿瘤基因组学

This dataset includes whole genome sequencing (WGS) data of 20 diagnostic, and 20 remission samples from 20 children/adolescents with acute myeloid leukemia (AML), treated at the Departments of Pediat

DataCite Commons2025-01-15 更新40

Helleday HRAS Project

资源简介：

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