Gene expression and chromatin accessibility of iLSCs vs iBlasts cells
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We identified two phenotypically and functionally distinct populations in AML-iPSC lines upon hematopoietic differentiation. A cell fraction with a hematopoietic stem cell (HSC) immunophenotype exhibiting adherent growth (iLSCs =samples A) and a fraction of more differentiated cells growing in suspension (iBlasts = samples S).We used RNA-seq and ATAC-seq analyses to identify molecular differences between the two populations.
创建时间:
2022-02-20



