The Vaccine Investigation and Online Information Network

The Vaccine Investigation and Online Information Network (VIOLIN) is a web-based central resource that integrates vaccine literature data mining, vaccine research data curation and storage, and curated vaccine data analysis for vaccines and vaccine candidates developed against various pathogens of high priority in public health and biological safety. The vaccine data includes research data from vaccine studies using humans, natural and laboratory animals. VIOLIN annotates, extracts and stores vaccine-related, peer-reviewed papers from PubMed. The curated vaccine-related information contains many categories such as general pathogenesis, protective immunity, vaccine preparation and characteristics, host responses including vaccination protocol and efficacy against virulent pathogen infections. All data within the database is edited manually and is derived primarily from peer-reviewed publications. The curated data is stored in a relational database and can be queried using various VIOLIN search programs.疫苗调查与在线信息网络（Vaccine Investigation and Online Information Network，VIOLIN）是一款基于Web的核心资源库，整合了疫苗文献数据挖掘、疫苗研究数据的整理与存储，以及针对公共卫生与生物安全领域各类高优先级病原体研发的疫苗及疫苗候选株的经人工整理疫苗数据分析功能。该数据库涵盖的疫苗数据包括针对人类、天然动物及实验动物开展的疫苗研究相关数据。VIOLIN会对PubMed收录的与疫苗相关的同行评议论文进行标注、提取与存储。经人工整理的疫苗相关信息包含多个类别，例如一般发病机制、保护性免疫、疫苗制备与特性、宿主应答（含疫苗接种方案及针对强毒病原体感染的防护效力）。该数据库内的所有数据均经过人工编辑，且主要来源于同行评议的学术出版物。经人工整理的数据存储于关系型数据库中，可通过多种VIOLIN检索程序进行查询。