Affect of Socs2 loss-of-function on liver regeneration
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Affect of Socs2 loss-of-function on liver regeneration
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2014-02-01
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Additional file 5: of Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics
Zip file containing the raw mRNA expression data generated from single cells used in this manuscript. Data were manually inspected for reactions with CT values above those for water (below the limit o
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Super-enhancer RNA seRNAHP promotes liver regeneration via upregulation of phosphoglycerate dehydrogenase and serine biosynthesis
A 70% partial hepatectomy (PHx) was performed on male super-enhancer Nacc1-SE (located near the Nacc1 gene) knockout mice to evaluate the contribution of Nacc1-SE to liver regeneration. In vitro, prim
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Macrophages trigger injury-induced hepatocyte reprogramming via IL-6/gp130/STAT3 axis [ChIP-Seq]. Macrophages trigger injury-induced hepatocyte reprogramming via IL-6/gp130/STAT3 axis [ChIP-Seq]
The liver is a pivotal organ possessing remarkable regenerative capacity. By employing murine liver injury models and lineage tracing strategy, recent studies have demonstrated that differentiated hep
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Additional file 2: of Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics
Collated single cell mRNA expression data used in this study. (TXT 111 kb)
Figshare2018-10-04 更新50
THE BILIARY EPITHELIUM GIVES RISE TO LIVER PROGENITOR CELLS BUT MAKES A MINOR CONTRIBUTION TO HEPATOCYTE REGENERATION AFTER LIVER INJURY. Mus musculus
We previously showed that severe liver diseases are characterized by expansion of liver progenitor cells (LPC), which correlates with disease severity. However, the origin and role of LPC in liver phy
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