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PDE10A in complex with the inhibitor AZ5

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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PDE10A in complex with the inhibitor AZ5 Descriptor: 2-(2'-ETHOXYBIPHENYL-4-YL)-4-HYDROXY-1,6-NAPHTHYRIDINE-3-CARBONITRILE, CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ... Authors: Bauer, U, Giordanetto, F, Bauer, M, OMahony, G, Johansson, K.E, Knecht, W, Hartleib-Geschwindner, J, Toppner Carlsson, E, Enroth, C, Sjogren, T. Deposit date: 2012-01-11 Release date: 2012-01-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of 4-Hydroxy-1,6-Naphthyridine-3-Carbonitrile Derivatives as Novel Pde10A Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012

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2012-01-11
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