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Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2‑Alkylazaarenes to <i>N</i>‑Boc Imines and Nitroalkenes

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NIAID Data Ecosystem2026-03-07 收录
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A chiral Pd­(II)–bis­(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkyl­aza­arenes to N-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields.

创建时间:
2016-02-20
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