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Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B

ChEBI2015-04-16 更新2026-07-21 收录

慢性乙型肝炎动物模型

免疫调节剂抗病毒疗效

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67935 数据链接链接失效反馈

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Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B

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创建时间：

2015-04-16

病毒药物疗效

慢性乙型肝炎动物模型

Ducks congenitally infected with duck hepatitis B virus (DHBV) were treated with the antiviral guanine nucleoside analog penciclovir for 12 or 24 weeks at a dosage of 10 mg/kg of body weight per day.

PubMed Central50

Intrahepatic transcriptional signature associated with response to interferon-a treatment in the woodchuck model of chronic hepatitis B. Marmota monax

慢性乙型肝炎动物模型

干扰素治疗响应转录组学

To define the intrahepatic cellular and molecular characteristics of the antiviral response to wIFN-alpha in woodchuck, the transcriptional profiles of woodchuck liver were studied by using RNASeq Ove

NIAID Data Ecosystem20

Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks

慢性乙型肝炎动物模型

肝脏转录组

Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks

ChEBI2012-04-10 更新10

Genome sequence of the Eastern woodchuck (Marmota monax) – a preclinical animal model for chronic hepatitis B. Genome sequence of the Eastern woodchuck (Marmota monax) – a preclinical animal model for chronic hepatitis B

慢性乙型肝炎动物模型

RNAseq基因表达谱

Gene expression profiling by RNAseq of lung, thymus, heart, pancreas, kidney, spleen and liver tissues from woodchuck as a preclinical animal model for chronic hepatitis B Overall design: In total 20

NIAID Data Ecosystem30

Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Spleen gene expression in uninfected, resolved and chronically infected woodchucks. Marmota monax

慢性乙型肝炎动物模型

病毒感染转录组

The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an anima

NIAID Data Ecosystem20

Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B

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