Transposable Element Single-Cell Analysis for pan-cancer Landscape Exploration

TE-SCALE是一个转座元件单细胞分析数据库，覆盖20种癌症类型的131万多个细胞，基于大量scRNA-seq数据构建。该数据库提供单细胞分辨率下的转座元件表达谱，分析肿瘤微环境中转座元件活性，识别肿瘤特异性转座元件，并支持深度功能探索。TE-SCALE is a single-cell analysis database for transposable elements (TEs). It covers over 1.31 million cells across 20 cancer types, and is constructed based on large-scale scRNA-seq datasets. This database provides TE expression profiles at single-cell resolution, analyzes TE activities in the tumor microenvironment, identifies tumor-specific TEs, and supports in-depth functional exploration.

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背景与挑战

背景概述

TE-SCALE是一个转座元件单细胞分析数据库，覆盖20种癌症类型的131万多个细胞，基于scRNA-seq数据构建。它提供单细胞分辨率下的转座元件表达谱，分析肿瘤微环境中转座元件活性，并识别肿瘤特异性转座元件，支持深度功能探索，适用于癌症研究的广泛分析。