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Transcriptome analysis of potential candidate genes and molecular pathways in Et-1-deficient mice with depigmentation

ChEBI2023-04-15 更新2026-07-12 收录

色素脱失分子机制

基因敲除模型转录组

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12835 数据链接链接失效反馈

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资源简介：

Transcriptome analysis of potential candidate genes and molecular pathways in Et-1-deficient mice with depigmentation

应用场景：

创建时间：

2023-04-15

干细胞衰老

基因敲除模型转录组

We collected significant amount of phenotypic and mechanistic data from a ATF4 knockout mouse model and demonstrated that HSC defects with an aging-like phenotype (expanded pool of phenotypical HSCs,

NIAID Data Ecosystem70

Hepatic transcriptome profiling of liver-specific Elovl6 knockout mice fed a high-sucrose diet

脂质代谢

基因敲除模型转录组

Elovl6 is a member of mammalian fatty acid elongase that is responsible for converting C16 saturated and monounsaturated fatty acids into C18 species. To understand the role of Elovl6 in liver, we gen

NIAID Data Ecosystem30

Gene expression data of the liver in hepatocyte-specific Phgdh knockout mice

肝脏代谢基因功能

基因敲除模型转录组

Live hepatocyte-specific Phgdh KO (LKO) mice were generated by introducing Albumin-Cre transgene into Phgdh flox/flox (Floxed) mice. LKO mice exhibited mild obesity and impaired glucose intolerance at

NIAID Data Ecosystem20

RNA-seq of bone marrow neutrophils from wild-type mice (C57BL/6) and CD40LG knockout mice.. RNA-seq of bone marrow neutrophils from wild-type mice (C57BL/6) and CD40LG knockout mice.

免疫细胞发育

基因敲除模型转录组

We aimed to investigate the effect of CD40L on neutrophil development by comparing the transcription profile of wild-type and knockout mice. Thus, we performed RNA-sequencing of bone marrow neutrophil

NIAID Data Ecosystem40

Adipocyte- Specific FFA2 Deletion Leads to Increased Adipose Inflammation and Is Associated with Altered Intestinal Lipid Handling

脂肪组织

基因敲除模型转录组

Obesity and related metabolic disorders are often characterized by chronic adipose tissue inflammation, driving systemic insulin resistance and general metabolic dysfunction. Free Fatty Acid Receptor

NIAID Data Ecosystem20

Transcriptome analysis of potential candidate genes and molecular pathways in Et-1-deficient mice with depigmentation

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