The CRISPR/Cas9 is a new system that can introduce site-specific double strand breaks. In this system, sequence specificity is achieved by 20-nucleotide RNA molecules that guild endonuclease to the sp
A missense mutation of collagen type VIII alpha 2 chain (COL8A2) gene leads to early onset Fuchs' endothelial corneal dystrophy (FECD), which can cause blindness through progressive loss of corneal en
