In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
Brain metastasis occurs in up to 40% of patients with non-small cell lung cancer (NSCLC). Considerable genomic heterogeneity exists between the primary lung tumor and respective brain metastasis; how
Natural killer T cells (NKTs) are a promising platform for cancer immunotherapy, but few genes involved in regulation of NKT therapeutic activity have been identified. To discover regulators of NKT fu