Background: Ion channels are key determinants for the function of excitable cells but little is known about their role and involvement during cardiac development. Earlier work identified Ca2+-activate

NIAID Data Ecosystem50

Genome-wide transcriptome analysis during differentiation of human embryonic stem (hES) cells into cardiac lineage

干细胞心脏分化

发育转录组学

hES cells display an excellent model to study the developmental mechanisms occuring in vivo both at genetic and epigenetic levels. hES cell line were subjected to global transcriptome analysis to stud

NIAID Data Ecosystem30

High-efficiency RNA-based reprogramming of human primary fibroblasts. Homo sapiens

诱导多能干细胞

RNA重编程技术

Induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine; however, their potential clinical application is hampered by the low efficiency of somatic cell reprogramming. Here

NIAID Data Ecosystem60

Dox-regulated Notch4 overexpression in mouse ES cells redirects hemagioblasts to a cardiac fate.

干细胞心脏分化

Notch信号通路

Previous studies have demonstrated that distinct progenitor subpopulations of mesoderm display tissue specific and vascular potential: hemangioblasts, a progenitor population capable of generating cel

NIAID Data Ecosystem30

File S1 - A Systemic Evaluation of Cardiac Differentiation from mRNA Reprogrammed Human Induced Pluripotent Stem Cells

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