RNA-seq analysis of SIRT6 and STAT6 regulated genes in intestinal epithelial cells (IECs)
收藏Alliance of Genome Resources2026-08-01 收录
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To investigate the roles of SIRT6 and IL4/IL13-STAT6 pathway in intestinal epithelium homeostasis, we generated IEC-specifc Sirt6 knockout mice and transgenic mice with IEC-specific overexpression of constitutively activated STAT6 (STAT6vt). IECs from these mice were isolated and RNA were extracted and performed RNAseq analysis. Comparative gene expression profiling analysis of RNA-seq data for IECs from Sirt6 knockout/LoxP mice and IECs from STAT6vt transgenic/WT mice
