CARDIO-LNCRNAS

CARDIO-LNCRNAS provides the landscape of the lncRNA transcriptome in human heart by systematically analysing the expression of all annotated and novel lncRNAs in heart relative to their expression in other human tissues. CARDIO-LNCRNAS summarizes all lncRNA transcripts from publicly available human transcriptome resources (156 heart samples and 210 samples from 29 other tissues) and systematically analysed all annotated and novel lncRNAs expressed in heart. A total of 7485 lncRNAs whose expression was elevated in heart (HE lncRNAs) and 453 lncRNAs expressed in all 30 analysed tissues (EIA lncRNAs) were extracted.CARDIO-LNCRNAS数据集通过系统性对比人类心脏中所有已注释及新发现的长链非编码RNA（long non-coding RNA, lncRNA）与其他人体组织的表达水平，绘制了人类心脏lncRNA转录组的全景图谱。该数据集整合了公开人类转录组资源中的全部lncRNA转录本，涵盖156份心脏样本以及来自29种其他组织的210份样本，并对心脏中表达的所有已注释及新发现的lncRNA进行了系统性分析。最终共提取得到7485种心脏高表达lncRNA（HE lncRNAs）以及453种在全部30种分析组织中均有表达的lncRNA（EIA lncRNAs）。

搜集汇总

背景与挑战

背景概述

CARDIO-LNCRNAS是一个专注于心血管系统长链非编码RNA（lncRNAs）的数据集，汇总了来自156个心脏样本和210个其他组织样本的公开转录组数据，分析了包括心脏高表达lncRNAs和全组织表达lncRNAs在内的特征。该资源提供了lncRNAs在基因组结构、发育动态、疾病关联等多方面的信息，旨在为用户提供心血管lncRNAs的全面视图。