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Interrelationships between replication infidelity and genome composition

ChEBI2014-08-25 更新2026-07-21 收录

DNA复制保真度

基因组稳定性分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56939 数据链接链接失效反馈

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Interrelationships between replication infidelity and genome composition

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创建时间：

2014-08-25

DNA复制保真度

胚胎干细胞分化

Purpose: we aimed to gain a genome-wide view of the dynamics in DNA methylation inheritance and define the factors associated with methylation fidelity. Methods: Using mouse embryonic stem cell (ES-E1

NIAID Data Ecosystem120

Bacillus subtilis PY79 mutation accumulation lines. Bacillus subtilis PY79

微生物突变

DNA复制保真度

Mutation accumulation was carried out in strains with and without DNA mismatch repair to determine the effect of sequence context on DNA polymerase error rate in vivo.

NIAID Data Ecosystem70

Genome-wide tracking of DNA polymerase III in E. coli

DNA复制保真度

核糖核苷酸基因组定位

We used steric gate variants of DNA polymerase III that allows increased amounts of ribonucleotides to be incorporated. Ribonucleotides incorporated into genomic is hydrolyzed by alkali. The generated

NIAID Data Ecosystem60

SNP analysis of human induced pluripotent stem cells. Homo sapiens

干细胞基因编辑

基因组稳定性分析

Human induced pluripotent stem cells (hIPSCs) represent a unique opportunity for regenerative medicine since they offer the prospect of generating unlimited quantities of cells for autologous transpla

NIAID Data Ecosystem70

LORE1 transpositions in regenerated plant populations.

转座子活性

基因组稳定性分析

#Transpositions were detected by SSAP (Sequence Specific Amplified Polymorphism) analysis amplifying 5′ fragments flanking LORE1 inserts.

NIAID Data Ecosystem60