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Genetic screens with Paf1 complex members in Saccharomyces cerevisiae
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2021-09-17
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plasmid-based BIR screen in S. cerevisiae. Saccharomyces cerevisiae
We used a plamsid-based assay to identify novel S. cerevisiae mutants with abnormal Break Induced Replication (BIR) efficiencies. We pooled the ca. 5000 yeast deletion mutants from the systematic dele
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of yeast strains used in study.
Nucleolar morphology is a well-established indicator of ribosome biogenesis activity that has served as the foundation of many screens investigating ribosome production. Missing from this field of stu
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Supressor screen results.
Eukaryotic chromosome segregation relies on the assembly of a bipolar machinery based on microtubules (MTs), named the mitotic spindle. Formation of the mitotic spindle follows a force balance mechani
Figshare2025-10-07 更新30
Yeast deletion strains synthetically sick with truncated LRRK2 or suppressors of the toxicity induced by truncated LRRK2.
The homolog category indicates yeast genes with clear human homologs.
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Additional file 9: of Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design
Sequence read information and raw counts from MiSeq data. (XLSX 3070 kb)
Figshare2016-12-15 更新40
