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资源简介：
Novel Cas12a, broad PAM editor
应用场景：
创建时间：
2023-11-22
相关数据集
PpCas9 from Pasteurella pneumotropica - a compact Type II-C Cas9 ortholog active in human cells. Part 2
Characterization Type II-C CRISPR Cas systems from Defluviimonas sp. 20V17 and Pasteurella pneumotropica. Illumina sequencing reads from PpCas9 specificity tests.
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Engineering a transposon-associated TnpB-omegaRNA system for efficient gene editing and phenotypic correction of a tyrosinaemia mouse model
Transposon-associated ribonucleoprotein TnpB is known to be the ancestry endonuclease of diverse Cas12 effector proteins from type-V CRISPR system. Given its small size (409 aa), it is of interest to
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Small Cas13 proteins enable compact RNA base editors
CRISPR-Cas13 systems have been developed for precise RNA editing, an attractive therapeutic strategy when temporary changes are desirable or DNA editing is not possible. We identified and characterize
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Homo sapiens Genome sequencing. Homo sapiens
Recently, base editors, composed of cytidine deaminase, Cas9 nickase (nCas9), and uracil DNA glycosylase inhibitor (UGI), have recently been developed to substitute a C at a target site with T without
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Study on genome editing tool
To develop a genome tool with high efficiency in in vivo study
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