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A Highly Diastereo- and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino Michael−Henry Reaction

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NIAID Data Ecosystem2026-03-06 收录
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Highly functionalized cyclopentanes with four stereogenic carbons including two quaternary stereocenters have been synthesized in excellent yields (90−95%) with complete diastereoselectivities and excellent enantioselectivities (88−96% ee) by the organocatalyzed asymmetric domino Michael−Henry reaction.

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2008-08-21
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