“P” indicates the statistical significance of the difference between treatment and negative control (n.s. = no statistically significant difference). “Treatment/negative control” represents the rati
aCovalent FAD is expressed in pmol covalend FAD mg of protein−1 and is an estimation of the total amount of succinate dehydrogenase enzyme present in the mitochondrial preparation, presented values ar
KAT-II (0.5 μg) was incubated at 37 °C for 10 min in a 50 μL reaction mixture containing 50 μM PLP, 5 mM α-ketoglutarate, 5 mM l-kynurenine in PBS, pH 7.4, with the inhibitor being studied (1–2000 μM)
aThe enzyme activity was measured using DNS method.bThe enzyme activity was measured using iodine method, thus the result can’t be directly compared with those measured using DNS method.NM: Not mentio
