THLE-2和 THLE-3细胞系是正常肝细胞用SV40大T抗原转染得到。 将含有SV40 T抗原的Bgl I-Hpa I片段的逆转录病毒载体导入兼嗜性包装细胞株PA317中生产病毒。 THLE-2 and THLE-3表达正常成人肝上皮细胞特征性的表型。当注射到无胸腺裸鼠中时，它们不成瘤，具有接近二倍体的核型，不表达甲胎蛋白。THLE-2 and THLE-3将benzo[a]pyrene, N
The cellular source for hepatocyte transplantation and liver regeneration in chronically hepatic diseases is a fundamental topic in liver biology. A successful therapeutic approach based on a benifici
