Global effects of 2-methoxyestradiol on smooth muscle cell hyperproliferation and vascular remodeling in atherosclerosis

ChEBI2008-12-30 更新2026-07-21 收录

动脉粥样硬化

血管平滑肌细胞增殖

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-12261 数据链接链接失效反馈

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资源简介：

Global effects of 2-methoxyestradiol on smooth muscle cell hyperproliferation and vascular remodeling in atherosclerosis

创建时间：

2008-12-30

Raw data

动脉粥样硬化

他汀类药物

Background: Matrix metalloproteinases (MMPs) play an important role in the pathophysiology of atherosclerosis. Reportedly, statins can decrease MMP activity in patients with atherosclerotic cardiovasc

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柠檬酸合酶和OGDH作为动脉粥样硬化在应激下的可能生物标志物

动脉粥样硬化

生物标志物

本数据集包括目的蛋白的含量、基因的表达量以及柠檬酸合酶和OGDH的酶活性以及免疫共沉淀（IP）测定和分子之间的相互作用，源于新西兰大白兔构建CS和AS动物模型的蛋白质组学和生物信息学获得的蛋白。对不同组间基因的分布、差异表达基因以及主要富集通路均采用R.studio软件，采用limma包、WGCNA包、ggplot2等进行数据分析，在肾上腺中鉴定了与CS和AS相关的两种最重要的枢纽蛋白（柠檬酸盐合

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circRNA expression profiles of mouse atherosclerotic and normal aortae by RNA-seq.. circRNA expression profiles of mouse atherosclerotic and normal aortae by RNA-seq.

动脉粥样硬化

环状RNA表达

To explore circRNAs expression profiles of mouse atherosclerotic model, we performed RNA-seq to detect circRNAs with potential functional role in atherosclerosis (AS). Overall design: CircRNA sequenci

NIAID Data Ecosystem60

Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group

心血管健康

动脉粥样硬化

Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group

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Single cell RNA sequencing of aortic CD45+ cells reveals aortic macrophage heterogeneity in mouse atherosclerosis

单细胞RNA测序

动脉粥样硬化

We have applied single cell RNA sequencing (scRNA-seq) as an unbiased transcriptomics to characterize aortic immune cells in atherosclerosis. The scRNA-seq analysis revealed macrophage heterogeneity a

NIAID Data Ecosystem60

Global effects of 2-methoxyestradiol on smooth muscle cell hyperproliferation and vascular remodeling in atherosclerosis

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