An Efficient One-Pot Approach to the Construction of Chiral Nitrogen-Containing Heterocycles under Mild Conditions
收藏NIAID Data Ecosystem2026-03-08 收录
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资源简介：
A new, general, and practical procedure for the highly enantioselective synthesis of functionalized nitrogen-containing heterocycles has been developed. The simple cyclic hemiaminals were directly catalyzed for the first time as nucleophiles in an enamine-based asymmetric conjugate addition reaction. The practical approach recycles the catalyst and solvent which make it possible for large-scale and diversity-oriented chemical production.
创建时间：
2016-02-13
