Tumor cells were microdissected from frozen sections of NLPHL and THRLBCL. RNA was amplified using the NUGEN WT-Ovation-One-direct-Kit. Samples were compared to tonsilar germinal center CD77 B cells.
To demonstrate aMT-exo could induce multi-antigenic response, PBS and aMT-exos were subcutaneously injected into mice. Then CD8 T cells were sorted out from lymph nodes and used for T cell receptor be
Primary central nervous system lymphoma (PCNSL) is a distinct extranodal lymphoma presenting with limited stage disease but variable response rates to treatment despite homogenous pathological present