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Full-Length Huntingtin Q54 And Q145 Expression And Purification – 29Th November 2017

Name: Full-Length Huntingtin Q54 And Q145 Expression And Purification – 29Th November 2017
Creator: University of Toronto, Structural Genomics Consortium
Published: 2017-11-29T00:00:00+08:00

Zenodo2017-11-29 更新2026-04-07 收录

蛋白质表达纯化

亨廷顿病机制研究

数据链接：

https://zenodo.org/record/1116436 数据链接链接失效反馈

官方服务：

资源简介：

Huntingtin structure-function open lab notebook

应用场景：

提供机构：

University of Toronto, Structural Genomics Consortium

创建时间：

2017-11-29

抗体工程

蛋白质表达纯化

Bacterial fusion proteins used for antibody generation, purification and characterization.

NIAID Data Ecosystem60

TBK1 suppresses mutant HTT induced toxicity and pathology in models of Huntington's disease

亨廷顿病机制研究

TBK1神经保护作用

Phosphorylation of the N-terminal domain of the Huntingtin (HTT) protein has emerged as an important regulator of its localization, structure, aggregation, clearance, and toxicity. However, validation

NIAID Data Ecosystem40

Figure A, Construction of the intracellular version of full-length CelA expression vector pDCW170. Figure B, PCR confirmation of expression vector transformation. Figure C, Diagram of the version of full-length extracellular CelA expression vector pDCW173. Figure D, Evidence for extracellular glycosylation of CelA (expanded). Figure E, Purification and verification of extracellular His-tagged CelA. Table A, Primers used in this study.

蛋白质表达纯化

分子载体构建

(DOCX)

NIAID Data Ecosystem10

Additional file 12 of TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration

亨廷顿病机制研究

神经胶质细胞互作

Additional file 12: Table S11. Isolation scheme of the DIA method.

DataCite Commons2024-09-11 更新60

Full-length huntingtin Q19, Q23, Q42 and Q54 expression and purification – 2018/04/23