Hippo通路在肝脏再生重塑中基因表达谱及新型蛋白质的机器及其功能

“Hippo通路在肝脏再生重塑中基因表达谱及新型蛋白质的机器及其功能”数据集：是由厦门大学所建立的一个国家重点研发项目“控制肝脏组织发育、再生重塑与大小的关键蛋白质机器”的重要成果的原始数据集，包含支持Hippo通路在肝脏再生重塑中基因表达谱及新型蛋白质的机器及其功能相关研究成果的蛋白质表达原始数据，细胞组织图像原始数据和统计图表原始数据。研究揭示Hippo通路新的下游靶基因如ITGB2 等并明确其生物学功能及作用机制。采集方案按对应实验具体要求的规范实施，设备为厦门大学生物医学仪器共享平台和浙江大学生命科学研究院共享技术服务平台相关仪器。

Dataset: Gene Expression Profiles, Novel Protein Machines and Their Functions of the Hippo Pathway in Liver Regeneration and Remodeling

This dataset is an original core dataset established by Xiamen University, which is an important achievement derived from the National Key R&D Program "Key Protein Machines Governing Liver Tissue Development, Regeneration, Remodeling and Size". It contains original raw protein expression data, original cellular tissue image data and original statistical chart data that support the research findings related to gene expression profiles, novel protein machines and their functions of the Hippo pathway during liver regeneration and remodeling. The study revealed novel downstream target genes of the Hippo pathway such as ITGB2, and clarified their biological functions and underlying action mechanisms. Data collection was conducted in strict accordance with the standardized requirements specified for each corresponding experiment, using instruments from the Biomedical Instrument Sharing Platform of Xiamen University and the Shared Technical Service Platform of the Life Sciences Institute of Zhejiang University.

搜集汇总

背景与挑战

背景概述

该数据集源自厦门大学承担的国家重点研发项目，提供了Hippo通路在肝脏再生重塑过程中的基因表达谱及新型蛋白质功能的原始数据，包括蛋白质表达、细胞组织图像和统计图表。研究揭示了Hippo通路的新下游靶基因如ITGB2，并阐明了其生物学功能与作用机制。数据采集遵循实验规范，依托厦门大学和浙江大学的共享技术平台完成。