Clinical Genome Resource

ClinGen was founded in 2013 by the National Human Genome Research Institute (NHGRI; https://www.genome.gov). ClinGen is a growing collaborative effort, involving three grants, six principal investigators and over 1,700 contributors from more than 40 countries. The Clinical Genome Resource (ClinGen) is a National Institutes of Health (NIH) funded initiative, building an authoritative central resource that defines the clinical relevance of genes and variants for use in precision medicine and research, aimed to increase the community’s knowledge about the relationship between genes and health. We are dedicated to building a knowledge base that defines the clinical relevance of genes and variants for use in precision medicine and research. We do this by first encouraging the sharing of genetic and health data by our key stakeholder groups: patients, clinicians, laboratories, and researchers. Explore our website to get to know our working groups, learn more about how we are meeting our goals and search our knowledge base.ClinGen于2013年由美国国家人类基因组研究所（National Human Genome Research Institute, NHGRI; https://www.genome.gov）创立。ClinGen是一项持续壮大的协作项目，涵盖3项资助拨款、6名首席研究员以及来自40余个国家的1700余名贡献者。临床基因组资源（Clinical Genome Resource, ClinGen）是由美国国立卫生研究院（National Institutes of Health, NIH）资助的专项计划，旨在搭建权威的核心资源库，明确基因与变异的临床相关性，以供精准医学与相关研究使用，从而提升学界对基因与健康之间关联的认知水平。我们致力于构建一套知识库，用以明确基因与变异的临床相关性，服务于精准医学与研究工作。为此，我们首先推动核心利益相关群体——患者、临床医师、实验室工作人员与研究人员——共享遗传与健康数据。欢迎访问我们的官方网站，了解我们的各个工作小组、更多项目目标的推进进展，并检索我们的知识库。

搜集汇总

背景与挑战

背景概述

Clinical Genome Resource（ClinGen）是一个由美国国立卫生研究院资助的协作项目，旨在构建一个权威的中央资源，定义基因和变异的临床相关性。该资源致力于增进对基因与健康关系的了解，以支持精准医学和科学研究。