WP5198 - Inflammatory bowel disease signaling - Homo sapiens

NIAID Data Ecosystem2026-05-02 收录

结肠炎机制

癌症信号通路

数据链接：

https://www.ndexbio.org/viewer/networks/5d1405b7-1439-11f0-9806-005056ae3c32 数据链接链接失效反馈

官方服务：

资源简介：

Pathway representing the inflammatory bowel disease showing steps leading to Crohn's disease and ulcerative colitis.

创建时间：

2025-04-17

Gene Expression Profiling of Ulcerative Colitis

结肠炎机制

差异基因表达分析

Through laser capture microdissection and microarray analysis combined with slightly modified RNA extraction and amplification. we could analyze the subtle differential expression between colon norm

NIAID Data Ecosystem60

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis

结肠炎机制

上皮屏障

Gasdermins are a family of structurally-related proteins originally described for their role in pyroptosis. Gasdermin B (GSDMB) is currently the least studied, and while its association with genetic s

NIAID Data Ecosystem30

Data_Sheet_4_Lnc-ITSN1-2, Derived From RNA Sequencing, Correlates With Increased Disease Risk, Activity and Promotes CD4+ T Cell Activation, Proliferation and Th1/Th17 Cell Differentiation by Serving as a ceRNA for IL-23R via Sponging miR-125a in Inflammatory Bowel Disease.zip

结肠炎机制

Th17细胞调控

Background: This study aimed to investigate long-non-coding RNA (lncRNA) expression profiles and the correlation of lnc-ITSN1-2 expression with disease risk, activity and inflammation, and its influen

NIAID Data Ecosystem30

BMI1 Maintains the Regulatory T cell Epigenomic Landscape to Prevent Inflammatory Bowel Disease (Microarray). BMI1 Maintains the Regulatory T cell Epigenomic Landscape to Prevent Inflammatory Bowel Disease (Microarray)

免疫表观遗传学

结肠炎机制

FOXP3+ Treg cells are expanded within the inflamed intestine of human Crohn’s disease, yet FOXP3-mediated gene repression within these cells is lost. The Polycomb repressive complexes play a role in F

NIAID Data Ecosystem30

OTUD3 prevents ulcerative colitis by modulating microbiota-mediated STING activation

猪肠道免疫学

结肠炎机制

Human intestinal Thy1+ mesenchymal cells are considered as heterogeneous population. We performed single cell RNA sequencing (scRNA-seq) to characterize fibroblast populations in the colonic mucosa.Li

NIAID Data Ecosystem30

WP5198 - Inflammatory bowel disease signaling - Homo sapiens

资源简介：

相关数据集